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KMID : 1134820150440111637
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Journal of the Korean Society of Food Science and Nutrition
2015 Volume.44 No. 11 p.1637 ~ p.1644
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Comparison of Biological Activities of Ethanol Extracts of Unripe Fruit of Bitter Melon (Momordica charantia L.) Cultivated in Hamyang, Korea
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Moon Jeong-Han
Choi Dong-Won
Kim Seong-Eun
Seomoon Ji-Hoon
Hong Su-Young
Kim Hyun-Kyu
Cho Kye-man
Song Jin
Kang Sang-Soo
Kim Kang-Hwa
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Abstract
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To develop health-functional food ingredients for improvement of diabetes, we examined biological activities, including total contents of polyphenols and flavonoids, antioxidant activity, and inhibition of α-glucosidase and pancreatic lipase activities of ethanol extracts from unripe fruit of Momordica charantia L. cultivated in Hamyang, Korea. Ethanol extracts were tested using different ethanol concentrations (0%, 30%, 50%, and 70%) and temperatures (50°C and 70°C). Experimental results showed that total polyphenol and flavonoid contents were achieved concentrations of 7.77 mg/g (tannic acid), 7.66 mg/g (gallic acid), and 10.66 mg/g (rutin). The hydroxyl radical scavenging, ABTS cation radical scavenging, and FRAP activities were 82.19%, 42.82%, and 0.19 under the same conditions, respectively. The highest inhibitory activities of α-glucosidase and pancreatic lipase were achieved in the 70% ethanol extract at 70°C. These results will be useful for development of health functional foods for anti-diabetes using 70% ethanol extract from unripe fruit of bitter melon
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KEYWORD
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Momordica charantia L., ethanol extract, α-glucosidase, pancreatic lipase, antioxidant
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